Common Names: garcinia cambogia, garcinia, Malabar tamarind, brindle berry
This Garcinia cambogia monograph provides basic information about garcinia cambogia—common names, usefulness and safety, and resources for more information.Source: https://nccih.nih.gov/
Garcinia cambogia (Malabar tamarind) is native to India and Southeast Asia. The rind of its fruit is used to flavor fish curries and preserve food.
The rind contains a chemical called hydroxycitric acid (HCA), which has been studied for its effect on appetite. Garcinia cambogia supplements with HCA are marketed for weight loss.
Garcinia cambogia has also been used as a dietary supplement for rheumatism, intestinal problems, and other conditions.
Garcinia cambogia is made into a tea, capsules, extracts, tablets, and lotion.
Garcinia Cambogia in Health Research
Garcinia cambogia has been studied for weight loss, but there aren’t a lot of recent, reliable studies on its effectiveness.
Garcinia Cambogia Research Summary
There’s no convincing evidence that garcinia cambogia will help you lose weight or control cholesterol.
In a very small study, women who were overweight were given garcinia cambogia extract or a placebo for 60 days. Triglyceride levels of the participants getting garcinia cambogia decreased by almost one-third. Triglycerides are a type of fat in blood and high levels may raise a person’s risk of developing heart disease. The participants’ HDL (the “good” cholesterol), LDL (the “bad” cholesterol), total cholesterol, and body weight didn’t change.
In another study, people who were overweight were given either garcinia cambogia extract, soy leaf extract, or a placebo. After 10 weeks, none of the supplements promoted weight loss or lowered total cholesterol.
Garcinia Cambogia Safety
Taking Garcinia cambogia for short periods (12 weeks or less) appears safe for most people.
Garcinia. Natural Medicines Web site. Accessed at naturalmedicines.therapeuticresearch.com on April 10, 2015. [Database subscription].
Greenway F. Garcinia. In: Coates PM, Betz JM, Blackman MR, et al., eds. Encyclopedia of Dietary Supplements. 2nd ed. New York, NY: Informa Healthcare; 2010:307-313.
Source: National Center for Biotechnology Information (NCBI)[Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; [1988] – [cited 2018 Apr 5]. Available from: https://www.ncbi.nlm.nih.gov/
Type 2 diabetes (T2D) is associated with the progression of cognitive dysfunction. Physical activity benefits cognition, but no evidence from randomized clinical trials has shown whether tai chi chuan has better long-term benefits than fitness walking in cognitive function for patients with T2D and mild cognitive impairment (MCI).
To conduct an ethnobotanical survey and document the traditional anticancer and antidiabetic plants used by the local tribes of Mizoram, Northeast India.
Type 2 diabetes mellitus (T2DM) accounts for >90% of the cases of diabetes in adults. Resistance to insulin action is the major cause that leads to chronic hyperglycemia in diabetic patients. T2DM is the consequence of activation of multiple pathways and factors involved in insulin resistance and β-cell dysfunction. Also, the etiology of T2DM involves the complex interplay between genetics and environmental factors. This interplay can be governed efficiently by lifestyle modifications to achieve better management of diabetes. The present review aims at discussing the major factors involved in the development of T2DM that remain unfocussed during the anti-diabetic therapy. The review also focuses on lifestyle modifications that are warranted for the successful management of T2DM. In addition, it attempts to explain flaws in current strategies to combat diabetes. The employability of phytoconstituents as multitargeting molecules and their potential use as effective therapeutic adjuvants to first line hypoglycemic agents to prevent side effects caused by the synthetic drugs are also discussed.
Obesity and diabetes are closely related metabolic disorders that have become major public health concerns worldwide. Over the past few decades, numerous studies have explored the underlying mechanisms of these disorders and identified various risk factors, including genetics, lifestyle, and dietary habits. Traditional Chinese Medicine (TCM) has been increasingly recognized for its potential to manage obesity and diabetes. Weight loss is difficult to sustain, and several diabetic therapies, such as sulfonylureas, thiazolidinediones, and insulin, might make it harder to lose weight. While lifestyle changes should be the primary approach for people interested in lowering weight, drugs are also worth investigating. Since some of the newer glucose-lowering medications that cause weight loss, such as glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and sodium-glucose cotransporter 2 inhibitors (SGLT2i), are additionally utilized or are under consideration for use as anti-obesity drugs, the frontier between glucose-lowering medication and weight loss drugs appears to be shifting. This review provides an overview of the literature on the underlying mechanisms of obesity and diabetes and the prospect of TCM in their management. We discuss the various TCM interventions, including acupuncture, herbal medicine, and dietary therapy, and their effects on metabolic health. We also highlight the potential of TCM in regulating gut microbiota, reducing inflammation, and improving insulin sensitivity. The findings suggest that TCM may provide a promising approach to preventing and managing obesity and diabetes. However, further well-designed studies are needed to confirm the efficacy and safety of TCM interventions and to elucidate their underlying mechanisms of action.
Plant-derived phytochemicals have been interested in as nutraceuticals for preventing the onset and progress of diabetes mellitus and its serious complications in recent years. Lam. is used in vegetables and in herbal medicine for its health-promoting properties against various diseases including diabetes mellitus. This study aimed to examine an effect of on diabetic hyperglycemia and dyslipidemia by meta-analyzing the current evidence of diabetic rodent models. Peer-reviewed studies written in English from two databases, PubMed and Embase, were searched to 30 April 2021. Studies reporting blood glucose or lipid levels in diabetic rodents with and without receiving extracts of were included. Forty-four studies enrolling 349 diabetic rodents treated with extracts of and 350 diabetic controls reported blood glucose levels. The pooled effect size was -3.92 (95% CI: -4.65 to -3.19) with a substantial heterogeneity. This effect was likely to be, at least in part, modified by the type of diabetic models. Moreover, diabetic hypertriglyceridemia and hypercholesterolemia were also significantly improved in diabetic rodent models treated with .
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Source: National Center for Biotechnology Information (NCBI)[Internet]. Bethesda (MD): National Library of Medicine (US), National Center for Biotechnology Information; [1988] – [cited 2018 Apr 5]. Available from: https://www.ncbi.nlm.nih.gov/
